Liver Disease

A study published in "Hepatology, the Journal of the American Association for the Study of Liver Diseases found that SAM-e could prevent liver disease used intravenously under the supervision of a doctor. SAM-e is also used for osteoarthritis pain and depression and may reduce symptoms of fibromyalgia. Doses are 400 to 800 mg twice a day for depression and 300-600 mg twice a day for osteoarthritis and 400 mg two to four times per day for fibromyalgia.